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guide · 7 min read

ATI Pharmacology Proctored Exam (CMS): What’s on It and How to Study

By David Zimmerman, RN and the NurseSavvy team

Clinically reviewed by David Zimmerman · RN · MSN, University of Arizona · BA in Education, Siena College

Product and source claims checked · How we review

The ATI Pharmacology proctored exam is one of ATI’s nine RN Content Mastery Series (CMS) exams, usually given near the end of the course. ATI’s 2019 guide lists 60 scored questions plus 10 unscored ones, at one minute each. You get a proficiency level, not a pass or fail, and Level 2 is a common target. Prepare by finding your gaps with a practice test, fixing those, then mixing.

What is on the ATI Pharmacology exam

ATI’s description of the Pharmacology practice test has three parts: the principles (pharmacodynamics, pharmacokinetics, safe administration, error prevention, age-specific considerations); prototype drugs for infection, pain and inflammation; and the drugs that act on each body system and the blood.

Here is the same subject laid out as NurseSavvy topics. Every topic has a cheat sheet, learning cards and original practice questions:

ATI Pharmacology CMS mapped to NurseSavvy: 112 topics in 33 areas. This is our map of the subject, not the exam’s blueprint.
AreaTopicsStart with
Pharmacology Fundamentals7Absorption & Bioavailability, Distribution, Metabolism & Excretion, Drug Interactions & Polypharmacy, +4 more
Beta-Blockers1Beta-Blockers
ACE Inhibitors & ARBs2ACE Inhibitors, ARBs
CCBs2Dihydropyridine CCBs, Non-Dihydropyridine CCBs
Diuretics3Loop Diuretics, Potassium-Sparing Diuretics, Thiazide Diuretics
Cardiac Glycosides1Digoxin
Antiarrhythmics3Adenosine, Amiodarone, Atropine
Anticoagulants3DOACs, Heparin, Warfarin
Antiplatelets & Thrombolytics2Antiplatelet Agents, Thrombolytics / Fibrinolytics
Nitrates & Statins2Nitroglycerin, Statins
Vasopressors2Dopamine, Norepinephrine & Vasopressin
Respiratory Drugs6Albuterol & Short-Acting Beta-2 Agonists, Inhaled Corticosteroids, Ipratropium & Anticholinergic Bronchodilators, +3 more
Antiepileptics4Antiepileptic General Principles, Levetiracetam & Newer Antiepileptics, Phenytoin / Dilantin, +1 more
Parkinson's & Neuro Drugs3Alzheimer's Disease Medications, Parkinson's Drugs, Levodopa/Carbidopa — Sinemet
Insulins3Insulin Administration Technique, Intermediate & Long-Acting Insulin, Rapid & Short-Acting Insulin
Oral & Non-Insulin Diabetes Meds4GLP-1 Receptor Agonists, Metformin / Glucophage, SGLT2 Inhibitors, +1 more
Thyroid & Corticosteroids3Antithyroid Drugs, Corticosteroids, Levothyroxine / Synthroid
Antidepressants4MAOIs, SNRIs, SSRIs, +1 more
Mood Stabilizers & Antipsychotics3Atypical Antipsychotics, Lithium, Typical Antipsychotics
Anxiolytics & Sedatives2Benzodiazepines, Non-Benzodiazepine Anxiolytics
Anti-Infective Foundations3Antibiotic Mechanisms of Action — Classification, Cephalosporins, Penicillins
FQ, AG, Vancomycin3Aminoglycosides, Fluoroquinolones, Vancomycin
Other Anti-Infectives7Amphotericin B, Anti-Tuberculosis (RIPE), Antiretroviral Therapy, +4 more
Pain Management Drugs7Acetaminophen, Adjuvant Pain Medications, Epidural Analgesia, +4 more
GI & Renal Drugs7Erythropoiesis-Stimulating Agents, H2 Receptor Blockers, Laxatives & Antidiarrheals, +4 more
Immune & Oncology Drugs5Calcineurin Inhibitors, Chemotherapy, Colony-Stimulating Factors, +2 more
OB/Maternal Drugs5Magnesium Sulfate, Medications & Pregnancy Safety, Oxytocin, +2 more
Pediatric Pharmacology1Pediatric Medication Administration
IV Therapy & Parenteral4Blood Transfusion, Central Line Care, IM, SubQ & Intradermal Injection, +1 more
Unit Conversion & Desired-Over-Have4Desired-Over-Have Formula, Med-Math Foundations, Ratio, Proportion & Dimensional Analysis, +1 more
IV Rate Calculation1IV Rate Calculation
Weight-Based Dosing & Safe Dose Range2Safe Dose Range Verification, Weight Conversion & mg/kg Dosing
Reconstitution & Infusion Drip Calculations3Continuous Infusion Calculations, Pediatric Dosage Calculation, Reconstitution & Dilution

Where students lose points

  • High-alert drugs. Heparin, warfarin, insulin, opioids and digoxin: the lab to check, the antidote, and the finding that means hold the dose.
  • Prototypes, not brand lists. Learn the class by its suffix and one prototype; our drug-suffix guide shows how.
  • Teaching. Many items are “which statement shows the teaching worked”, so know the one or two things a patient must do or report for each class.
  • Narrow-range drugs. Lithium, magnesium sulfate and the aminoglycosides all ask you to spot toxicity early.

A study plan for the ATI Pharmacology CMS

Pick the weeks you have left. The plan splits the subject into even weeks and keeps the last one for mixed practice.

Ready-made study plan

ATI Pharmacology CMS, week by week

Weeks until the exam

112 NurseSavvy topics across 33 areas. About 10 topics a study day, six days a week, then a week of mixed practice.

  1. Week 1 · 55 topics

    Pharmacology Fundamentals · Beta-Blockers · ACE Inhibitors & ARBs · CCBs · Diuretics · Cardiac Glycosides · Antiarrhythmics · Anticoagulants · Antiplatelets & Thrombolytics · Nitrates & Statins · Vasopressors · Respiratory Drugs · Antiepileptics · Parkinson's & Neuro Drugs · Insulins · Oral & Non-Insulin Diabetes Meds · Thyroid & Corticosteroids · Antidepressants

  2. Week 2 · 57 topics

    Mood Stabilizers & Antipsychotics · Anxiolytics & Sedatives · Anti-Infective Foundations · FQ, AG, Vancomycin · Other Anti-Infectives · Pain Management Drugs · GI & Renal Drugs · Immune & Oncology Drugs · OB/Maternal Drugs · Pediatric Pharmacology · IV Therapy & Parenteral · Unit Conversion & Desired-Over-Have · IV Rate Calculation · Weight-Based Dosing & Safe Dose Range · Reconstitution & Infusion Drip Calculations

  3. Week 3 · mixed practice

    Questions across every area, a timed practice test early in the week, then only the topics you missed. Nothing new the night before.

How to study for it, in order

  1. Measure first. Take Practice A with rationales off, the way the proctored exam feels. ATI itself says practice scores are not built to predict the proctored score, so treat it as a map of what you missed, not a forecast.
  2. Fix the misses, not the whole book. Work the Focused Review it builds and write out the key points for each missed topic (many schools assign “three critical points” or ATI’s Active Learning Templates). Then take Practice B with rationales on.
  3. Relearn by system, then mix. Learn each weak area with short recall sessions (on NurseSavvy, the topic’s cards and cheat sheet), then answer mixed questions so you practice choosing the area, not just answering inside it.
  4. Spend the last days on priority and safety. These exams are written in the NCLEX style: what do you do first, which finding do you report, what does the teaching need to correct. Our priority-question guide covers the reasoning.
  5. Stop the night before. Sleep is the last study session.

What score do you need?

ATI reports a proficiency level, not a pass or fail. Level 2 means ATI is fairly certain you meet the NCLEX-RN standard in pharmacology. It is the level ATI’s own research counts as proficient and a common school target, though some schools ask for Level 3. ATI does not publish the percent each level needs; it varies by exam and version, so ignore the numbers on forums. The full picture is in ATI proficiency levels explained.

How much it counts is your school’s call. At the schools whose policies we read, the ATI part of a course grade was 10% or less, often with points for the practice tests and Focused Review as well as the proctored level.

A ready-made ATI Pharmacology CMS plan

All 112 topics in one plan, with learning cards and original practice questions. Free; narrow it with your study guide any time.

Start this plan

New to ATI’s exams? Start with what the Content Mastery Series is. Looking for free practice? Read what is actually free.

ATI, Content Mastery Series and Comprehensive Predictor are trademarks of Assessment Technologies Institute, LLC. HESI is a registered trademark of Elsevier. Kaplan is a trademark of Kaplan, Inc. NCLEX is a registered trademark of the National Council of State Boards of Nursing. NurseSavvy is not affiliated with or endorsed by these companies, and every NurseSavvy practice question is original.

Common questions

How many questions are on the ATI Pharmacology proctored exam?

ATI’s 2019 educator guide lists 60 scored questions plus 10 unscored pretest questions, with one minute allowed per question. ATI does not publish counts for the current versions, so check with your instructor.

What score do I need on the ATI Pharmacology exam?

ATI reports a proficiency level, not a pass or fail. Level 2, which ATI describes as fairly certain to meet the NCLEX-RN standard in that content area, is a common target; some schools ask for Level 3. The percent needed for each level is not public and differs by exam and version.

How do I study for the ATI Pharmacology proctored exam?

Take Practice A with rationales off to find your gaps, work the Focused Review on the topics you missed, take Practice B with rationales on, then finish with mixed questions on priority and safety.

Are there free ATI Pharmacology practice questions?

ATI does not post free practice questions for its Content Mastery Series exams; your school provides Practice A and B. NurseSavvy has free, original NCLEX-style questions on the same subject, organized the same way.

Start a ready-made ATI Pharmacology CMS plan.

Every topic on the exam, with learning cards and original practice questions. Free. Upload your instructor’s study guide to narrow it.

Start this plan