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Desired-Over-Have Formula

Desired over have — sometimes written D/H x Q — is the single formula behind most oral and injectable dose calculations. Desired is what the prescriber ordered. Have is the strength printed on the label. Quantity is the volume or number of tablets that labelled strength comes in. Divide desired by have, multiply by the quantity, and the result is the amount to administer. Two things make it go wrong: running it before the units match, and misreading the quantity as the size of the container rather than the volume the strength is stated in.

Desired = the ordered dose Hallmark
Have = the strength on the label Hallmark
Quantity = the volume that strength comes in Hallmark
5 mL on a label reading 250 mg per 5 mL — not the bottle size
Quantity is 1 for a tablet Hallmark
which is why tablet problems look like plain division
Both dose figures must share a unit Hallmark
The answer carries the quantity's unit
millilitres in, millilitres out

Worked example: 375 mg ordered, label reads 250 mg per 5 mL

  1. Desired375 mg
  2. Have250 mg
  3. Quantity5 mL
  4. Divide then multiply375 / 250 x 5
  5. Answer7.5 mL
Compare the answer with the strength you have Hallmark
if desired is larger than have, the answer must exceed the quantity
Check the tablet can be split the way the answer requires Hallmark
only scored tablets halve; nothing splits into thirds
Have a second nurse verify high-alert calculations
Re-read the label rather than working from memory
Measure the calculated volume with the supplied syringe Hallmark
Do not split a tablet that is not scored
Check that a refill has the same strength as the last bottle Hallmark
a new strength changes the volume to give
Ask before halving a capsule or extended-release tablet
Report Nowescalate immediately
An answer that needs a tablet cut into thirds Hallmark
An intramuscular volume larger than the site can hold
An answer far larger than the quantity on the label Hallmark
usually an unmatched unit
A refill bottle with a different strength than expected
Any high-alert dose not independently double-checked

Clinical Pearl

Desired over have, times the quantity it comes in. Match the units first, or the formula will hand you a wrong answer with total confidence.

NurseSavvy™·nursesavvy.com

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