Nurse Practitioner Salary in Mississippi: $124,730 Median (May 2025)
Nurse practitioners in Mississippi earn a median of $124,730 per year — $59.96 an hour — $7,570 below the national NP median of $132,300, ranking #47 of 51 states and D.C. The middle 80% of Mississippi NPs earn between $98,780 and $156,830. Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), May 2025 — the federal wage survey, not job-board self-reports.
Mississippi NP pay range (May 2025)
Dark band = middle 50% of Mississippi NPs (25th–75th percentile). Light band = middle 80%. New NPs typically start near the left edge.
NP vs RN Pay in Mississippi
The median NP in Mississippi out-earns the median RN by $47,640 per year (62%). Same state, same license underneath — the difference is the graduate degree and the scope that comes with it.
Compare Mississippi With Any State
Weighing a move, telehealth, or a compact-state license? Put Mississippi side by side with any other NP market.
| May 2025 BLS | Mississippi | Texas |
|---|---|---|
| Median annual salary | $124,730 | $131,670 |
| Median hourly wage | $59.96/hr | $63.31/hr |
| Entry-level range (10th pct) | $98,780 | $96,880 |
| Experienced (75th pct) | $134,020 | $147,660 |
| Top earners (90th pct) | $156,830 | $161,980 |
| NPs employed | 4,690 | 25,970 |
The NP path starts with an RN license
Every NP passed the NCLEX first. If you’re earlier on the ladder: compare Mississippi’s board-approved nursing programs by real first-time pass rates, and see the full earning ladder from CNA to CRNA.
Frequently Asked Questions
How much do nurse practitioners make in Mississippi?
NPs in Mississippi earn a median of $124,730 per year — $59.96 per hour — $7,570 below the national NP median of $132,300 (BLS May 2025). That ranks Mississippi #47 of 51 states and D.C. by median NP pay.
How much more do NPs make than RNs in Mississippi?
The median NP in Mississippi earns $124,730 versus $77,090 for the median RN — a difference of $47,640 per year (62%). The step up requires a master's or doctoral NP program on top of the RN license.
What is a starting NP salary in Mississippi?
New NPs generally start near the lower percentiles: in Mississippi, the 10th percentile is $98,780 and the 25th percentile is $106,660. Most NPs move toward the $124,730 median within their first several years of practice.
How many nurse practitioners work in Mississippi?
4,690 nurse practitioners are employed in Mississippi per the BLS May 2025 estimates.