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Pediatrics · Topic 25 of 42

Coarctation of the Aorta

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Pediatrics · cardiac

Coarctation of the Aorta

A narrowing of the aorta just past the left subclavian artery: pressure runs high in the arms and low in the legs. A newborn with critical coarctation crashes as the ductus closes.

01 · Newborn crashShock as the ductus closes: prostaglandin E1
02 · The hallmarkArm BP higher than legs, weak femoral pulses
03 · SignificantArm-to-leg systolic gradient over 20 mmHg
01

Why it happens

The aorta narrows just past the left subclavian artery

Narrowing sits where the ductus arteriosus joins the aorta
Arms: high BP, bounding radial and brachial pulses
Legs: low BP, weak, delayed or absent femoral pulses

Coarctation makes up about 6–8% of congenital heart defects and is about twice as common in males.

02

Linked conditions

Think coarctation with Turner syndrome or a bicuspid aortic valve

Associated
Turner syndromeBicuspid aortic valve

Coarctation occurs in about 10–20% of clients with Turner syndrome; a bicuspid aortic valve is found in about 45–62% of clients with coarctation.

03

What you'll see

Arms high, legs low — the newborn can crash, the older child can look well

Arm BP higher than leg BP hallmark
Bounding radial and brachial pulses
Weak, delayed or absent femoral pulses hallmark
Newborn: poor feeding, shock, metabolic acidosis critical coarctation
Older child: headaches, nosebleeds (epistaxis), dizziness
Leg cramps with exercise (claudication), cool feet or legs

Older children may have no symptoms at all. Murmur: systolic ejection at the upper left sternal border, often loudest over the back between the shoulder blades. Rib notching on chest X-ray (enlarged collateral arteries) is seldom seen before age 5.

04

Assessment & numbers

Take BP in all four extremities

Take blood pressure in all four extremities
Compare brachial with femoral pulses
Normal child: legs read the same as or higher than arms
Significant: arm-to-leg systolic gradient over 20 mmHg

In newborns, single limb readings vary widely; an isolated 20 mmHg difference may be measurement noise, and echocardiography confirms or excludes coarctation.

05

Red flags

Newborn with poor feeding, shock or metabolic acidosis expect PGE1 now
Apnea while on alprostadil boxed warning
Arm BP higher than leg BP or weak femoral pulses report now
Weak leg pulses after repair residual narrowing?

Rarer after repair, report: abdominal pain with high BP (mesenteric arteritis, postcoarctectomy syndrome), leg paralysis (spinal cord ischemia — check leg movement), hoarseness (recurrent laryngeal nerve injury).

06

Treatment

Critical coarctation in a newborn — right now
1
Prostaglandin E1 to reopen the ductus
→
2
Continuous breathing monitoring
→
3
Ventilation equipment ready
Prostaglandin E1reopens the ductus
alprostadil

Give immediately for critical coarctation

Apnea, usually within the first hour
Surgeryusual in newborns and infants

Resection with end-to-end anastomosis

Balloonolder children or re-narrowing

Balloon angioplasty, often with a stent

After repairrebound (paradoxical) hypertension

Check BP often; give IV antihypertensives as ordered

Check femoral and pedal pulses too
Heart failure care and long-term numbers
Newborn in heart failure: care as for any infant in heart failurewhile awaiting repair
Long-term hypertension in about 25–68% even after repairre-coarctation is more likely when repair was done in the newborn period
07

Nursing priorities

Newborn in shock as the ductus closes: expect prostaglandin E1 now
On alprostadil: monitor breathing continuously, ventilation ready
Take four-extremity BP; compare brachial with femoral pulses
After repair: check BP frequently for rebound hypertension
After repair: check leg pulses, color, warmth and capillary refill
08

Teach the family

Lifelong cardiology follow-up with regular BP checks
Re-coarctation and high BP can appear years after repair

No routine antibiotics before dental work for unrepaired coarctation; after repair with prosthetic material or a stent, prophylaxis is given only for the first 6 months.

Pearl

Arms high, legs low — take BP in all four extremities and compare brachial with femoral pulses. A newborn who crashes as the ductus closes needs prostaglandin E1 now. After repair, expect rebound hypertension.

Sources · Coarctation of the Aorta (Merck Manual Professional) · Coarctation of the aorta (MedlinePlus) · Coarctation of Aorta in Children (Cureus, PMC) · Prostin VR Pediatric (alprostadil) label (DailyMed) · Abdominal pain after stenting for aortic coarctation (J Vasc Surg Cases, PMC) · Variability of four limb blood pressure in normal neonates (Arch Dis Child, PMC) · Oscillometric blood pressures in healthy children and aortic coarctation (Pediatrics) · Antibiotic Prophylaxis Prior to Dental Procedures (ADA) · Follow your facility's protocol for alprostadil.

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