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Pediatrics · Topic 15 of 32

Autism Spectrum Disorder

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Pediatrics · neurodevelopmental

Autism Spectrum Disorder

Lasting differences in social communication plus restricted, repetitive behaviors, starting in early childhood. Screen early, refer fast, and adapt care to keep the child calm and safe.

01 · Refer nowAny loss of words or social skills, any age
02 · The screenM-CHAT-R/F at 18 and 24 months
03 · At the bedsideQuiet room, home routine, one step at a time
01

What it is

Two core features, starting in early childhood

Deficits in social communication and interaction
Restricted, repetitive behaviors or interests
A spectrum: support needs range from level 1 to 3
Vaccines do not cause autism

A Danish cohort of over 650,000 children found MMR vaccination does not raise autism risk.

02

Risk factors

A sibling with ASD raises the risk

Family and genes
Sibling with ASDFragile X syndromeMale sex
Parents and birth
Older parentsBirth complications
03

What you'll see

Social, repetitive and sensory signs

Poor or no eye contact social
No response to name by 9 months
No pointing to show interest by 18 months
Lines up toys, upset by minor changes sameness
Echolalia (repeating words or phrases)
Hand flapping, rocking, spinning
Sensory over- or under-response to sound, light, touch

Common co-occurring conditions: seizures, constipation and other GI problems, sleep problems, ADHD-like behavior and anxiety.

04

Screening red flags

A red flag means refer now — never wait and see

No babbling or gestures (pointing, waving) by 12 months
No single words by 16 months
No 2-word phrases by 24 months
Any loss of language or social skills, at any age
M-CHAT-R/F autism screen at 18 and 24 months
A positive screen means referral, not a diagnosis
05

Red flags

Child missing from the room or unit elopement
Head banging or biting that causes injury self-injury
New loss of words or social skills refer now
Weight gain or rising glucose on risperidone or aripiprazole metabolic

About half of children with autism try to wander or bolt from supervision. Electronic tracking devices are linked to less frequent elopement.

06

Treatment

Early interventionimproves outcomes

Start intensive behavioral therapy early, such as ABA

Refer before a formal diagnosis if needed
Therapiescommunication and daily skills

Speech and occupational therapy

Irritabilityaggression, self-injury, tantrums
risperidone aripiprazole

Monitor weight, glucose and lipids

Sedation; risperidone raises prolactin
Medication details
No medication treats the core features of autism
Labeled ages: risperidone 5–17, aripiprazole 6–17
07

Nursing priorities

Keep the child safe from wandering and self-injury
Ask parents about triggers, calming strategies and communication
Give a quiet room; silence or remove unneeded alarms
Keep the home routine for meals and bedtime
Prepare each step with a visual schedule and concrete words
Use consistent caregivers and cluster care
08

Teach the family

Vaccines do not cause autism
A positive screen means evaluation, not a diagnosis
Start early intervention as soon as it is offered
Plan for wandering with close supervision
Keep weight and lab checks on risperidone or aripiprazole
Use support groups and community services

Assess caregiver stress and siblings' needs, and include parents in every care plan.

Pearl

Lower the input and keep the routine — a quiet room, the home schedule, one step at a time. Ask the parents what works. Any loss of skills at any age: refer now.

Sources · Autism Spectrum Disorder (StatPearls) · Psychiatric-Mental Health Nursing 23.3 Autism Spectrum Disorder (OpenStax) · Identification and Evaluation of Children With ASD (AAP) · Identification, Evaluation, and Management of Children With ASD (AAP) · Clinical Screening for ASD (CDC) · Signs and Symptoms of ASD (CDC) · Best Practices for Hospitalized Pediatric Patients with ASD (CHOC Children's) · Elopement in Children With ASD (Pediatrics) · Electronic Tracking Devices and Elopement (J Dev Behav Pediatr) · MMR Vaccination and Autism (Annals of Internal Medicine) · Risperdal label (DailyMed) · Abilify label (DailyMed) · Follow your facility's protocol for elopement prevention.

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