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Maternal & Newborn · Topic 47 of 48

TORCH Infections in Pregnancy

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Maternity · antepartum

TORCH Infections in Pregnancy

Infections that pass to the fetus and can cause miscarriage, stillbirth or birth defects. The nurse's job is prevention, screening and timing.

01 · Herpes at laborLesions or prodrome at labor: cesarean
02 · Rubella ruleMMR is live: vaccinate after birth
03 · ToxoplasmosisSomeone else changes the cat litter
01

What TORCH stands for

Infections that cross to the fetus

T — Toxoplasmosis (cat feces, undercooked meat, soil)
O — Other: syphilis, varicella, parvovirus B19, HIV
R — Rubella (worst in the first 12 weeks)
C — Cytomegalovirus (CMV), the most common congenital infection
H — Herpes simplex (exposure during birth)

CMV affects about 1 in 200 newborns; CDC calls it the most common infectious cause of birth defects in the US.

02

What it does to the fetus and newborn

Each infection has its signature

Rubella: deafness, cataracts, heart defects hallmark
CMV: hearing loss, even after a passed hearing screen hallmark
Parvovirus B19: severe fetal anemia, hydrops fetalis
Syphilis: stillbirth, preterm birth, congenital syphilis
Herpes: neonatal herpes from lesions at birth

Most newborns with congenital CMV look well at birth. Congenital toxoplasmosis can cause vision loss, hearing loss and developmental delay, and many infected newborns have no signs at birth. Early-pregnancy varicella rarely causes congenital varicella syndrome (skin scarring, limb defects).

03

Screening & tests

First prenatal visit: rubella titer, RPR/VDRL, HIV

Rubella titer at the first prenatal visit
Syphilis screen (RPR or VDRL) at the first prenatal visit
HIV test for every pregnant patient at the first visit
Regular hearing checks for a newborn with congenital CMV

There is no routine CMV screening in pregnancy; a newborn is tested within 2–3 weeks of birth (urine preferred). HIV care in pregnancy is taught in the HIV topic.

04

Red flags

Genital lesions or tingling and burning at the onset of labor plan cesarean
MMR or varicella vaccine ordered during pregnancy live vaccine
Non-immune patient exposed to chickenpox VariZIG within 10 days
Parvovirus B19 exposure or symptoms in pregnancy report now
Maternal chickenpox rash 5 days before to 2 days after birth newborn at risk
05

Treatment

Cesareanherpes at labor

Cesarean birth for active lesions or prodrome at labor

Suppressionhistory of genital herpes
acyclovir valacyclovir

Suppressive acyclovir or valacyclovir from 36 weeks

Penicillinsyphilis
benzathine penicillin G

Penicillin G is the only recommended treatment — benzathine IM for most stages; desensitize if allergic

Vaccinesafter birth
MMR vaccine varicella vaccine

Vaccinate a non-immune patient after birth

Avoid pregnancy for 4 weeks after MMR
Exposures in pregnancy
Chickenpox exposure, non-immune: VariZIG as soon as possible
VariZIG works within 10 days of exposure
Parvovirus B19: the fetus is monitored for anemia
Most fetal parvovirus infections resolve without harm
06

Nursing priorities

Assess for genital lesions or prodrome on admission in labor
Check the rubella titer; plan postpartum MMR if non-immune
Teach someone else to change the cat litter
Teach handwashing after diapers and a young child's saliva
Report chickenpox or parvovirus B19 exposure promptly
07

Teach your patient

Have someone else change the cat litter
If you must change it, wear disposable gloves and wash hands
Cook meat to a safe temperature; use a food thermometer
Rinse fruits and vegetables; wear gloves when gardening
Wash hands after diapers or a young child's saliva or urine
Don't share food, utensils, cups or pacifiers with a child
Avoid pregnancy for 4 weeks after the MMR vaccine
Breastfeeding is safe after the postpartum MMR vaccine

Toxoplasma in cat feces becomes infectious 1–5 days after it is shed, which is why the litter is changed daily.

Pearl

TORCH care is prevention and timing: someone else changes the litter, wash hands around a toddler's diapers and saliva, MMR waits until after birth, and herpes lesions or prodrome at labor mean cesarean.

Sources · Maternal-Newborn Nursing 12.2 Conditions Limited to Pregnancy (OpenStax) · Maternal-Newborn Nursing 11.1 First Prenatal Visit (OpenStax) · People at Increased Risk for Toxoplasmosis (CDC) · Preventing Toxoplasmosis (CDC) · Congenital CMV Infection (CDC) · Guidelines for Vaccinating Pregnant Women (CDC) · Pink Book Chapter 20 Rubella (CDC) · STI Treatment Guidelines Genital Herpes (CDC) · STI Treatment Guidelines Congenital Syphilis (CDC) · Increased Human Parvovirus B19 Activity, HAN 00514 (CDC) · Clinical Guidance for People at Risk for Severe Varicella (CDC) · Follow your facility's protocol for prenatal screening.

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