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Biology basics & diversity of life · Topic 3 of 17

Microorganisms, Infectious Disease & Immunity

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Biology · microbes & disease

Microorganisms, Infectious Disease & Immunity

Bacteria, viruses, fungi and protists can cause disease; antibiotics work on bacteria only, while vaccines are the main defense against viruses.

01 · VirusVirus = DNA or RNA in a protein coat
02 · TreatmentAntibiotics: bacteria yes, viruses no
03 · ResistanceMisused antibiotics breed resistant bacteria
01

What it is

Pathogen = a disease-causing agent: bacteria, viruses, fungi, protists must know
Viruses multiply only inside a host cell, using the cell's machinery must know
Viral disease: prevented mainly by vaccines; a few antiviral drugs exist
Vaccine = weakened, killed or partial pathogen that builds immunity
Overused or unfinished antibiotics leave resistant bacteria to multiply
Bacterial diseases: strep throat, plague, botulism, some E. coli
Viral diseases: colds, flu, measles, chickenpox, hepatitis, HIV
Fungal infections: athlete's foot, ringworm (a fungus, not a worm), thrush
Protist diseases: malaria (Plasmodium, via mosquitoes), sleeping sickness
02

Parts & jobs

Virus = DNA or RNA inside a protein coat (capsid); far smaller than bacteria must know
03

Step by step

Spread: contact, droplets, objects (fomites), food/water/air, vectors
04

The rules

Antibiotics treat bacterial infections — they do not work on viruses must know
05

Don't confuse

Bacteria are living cells that reproduce on their own; viruses are not
Innate defense = fast, nonspecific; adaptive = specific, with memory
06

Bacterium or virus?

Commonly confused
BacteriaViruses
Made ofA living prokaryotic cellDNA or RNA in a protein coat
ReproducesOn its ownOnly inside a host cell
SizeAbout 100× largerMuch smaller
AntibioticsWorkDo not work
Main defenseAntibiotics (used carefully)Vaccines; a few antivirals
Pearl

Antibiotics are for bacteria; viruses need a vaccine or an antiviral.

Sources · OpenStax Concepts of Biology §17.1 Viruses · OpenStax Concepts of Biology §13.1 Prokaryotic Diversity (pathogens, the antibiotic crisis) · OpenStax Concepts of Biology §13.3 Protists (human pathogens) · OpenStax Concepts of Biology §13.4 Fungi (human pathogens) · OpenStax Microbiology §16.3 Modes of Disease Transmission · CDC — Antibiotic Use: About (antibiotics do not work on viruses) · OpenStax Concepts of Biology §17.2 Innate Immunity · OpenStax Biology 2e §21.3 Prevention and Treatment of Viral Infections · OpenStax Concepts of Biology §17.3 Adaptive Immunity · Odessa College Library — HESI A2 guide (Biology list: infectious diseases, immune system) · Built from the verified NurseSavvy HESI A2 fact map (facts reviewed 2026-10-16). HESI is a trademark of Elsevier; NurseSavvy is not affiliated with Elsevier.

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