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Support & movement · Topic 4 of 18

Integumentary System

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Anatomy · integumentary system

Integumentary System

Skin is epidermis over dermis, with the hypodermis beneath; with hair, nails and glands it protects, cools, senses and makes vitamin D.

01 · Layers, outside inEpidermis → dermis → hypodermis
02 · Four jobsProtect · cool · sense · make vitamin D
03 · Vitamin DSunlight on skin → vitamin D
01

What it is

Integumentary = skin + hair, nails, sweat and oil glands must know
Skin jobs: protect, regulate temperature, sense, make vitamin D must know
Keratin = the tough, water-resistant protein of skin, hair, nails
Melanocytes make melanin: skin color and UV protection
02

Parts & jobs

Outside in: epidermis → dermis → hypodermis (subcutaneous) must know
Epidermis = stratified squamous epithelium with no blood vessels must know
Dermis holds the vessels, nerves, follicles and glands must know
Hypodermis = fat layer that insulates, cushions and anchors the skin
Stratum basale = deepest epidermal layer, where new cells are made
Stratum corneum = surface layer of dead keratinized cells
Sebaceous glands secrete sebum, an oil that lubricates skin and hair
Eccrine glands: watery sweat everywhere that cools the body
Apocrine glands: armpit and groin, thicker sweat, body odor
Hair = dead keratin cells from a follicle; arrector pili lifts it
Nails = keratin plates that protect fingertips and toe tips
03

Step by step

Hot: dermal vessels dilate + sweat; cold: vessels constrict
UV light on skin → vitamin D → calcium absorption for bone
04

Eccrine or apocrine sweat gland?

Commonly confused
EccrineApocrine
WhereAll over the skin; most on palms, soles, foreheadArmpits and groin
Duct opens ontoA pore on the skin surfaceA hair follicle
SweatWatery (mostly water and salt)Thicker, with organic compounds
Main job / resultCooling by evaporationBody odor once bacteria break it down
05

More detail

Show 5 more facts
Strata, deep → top: basale, spinosum, granulosum, lucidum (thick skin only), corneum
Dermis = papillary layer (fingerprint ridges) over the reticular layer
Meissner corpuscles = light touch; Pacinian corpuscles = vibration
Skin makes vitamin D; liver then kidneys activate it (calcitriol)
Lunula = pale crescent at nail base; cuticle = eponychium
Pearl

Epi- means upon and hypo- means below: epidermis on top, dermis in the middle, hypodermis underneath.

Sources · OpenStax Anatomy & Physiology 2e §5.1 Layers of the Skin · OpenStax Anatomy & Physiology 2e §5.2 Accessory Structures of the Skin · OpenStax Anatomy & Physiology 2e §5.3 Functions of the Integumentary System · Union Test Prep — HESI A&P study guide, page 2 (integumentary system) · Built from the verified NurseSavvy HESI A2 fact map (facts reviewed 2026-10-16). HESI is a trademark of Elsevier; NurseSavvy is not affiliated with Elsevier.

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