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Respiratory · Topic 14 of 19

Mechanical Ventilation

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Respiratory · critical care

Mechanical Ventilation

A ventilator delivers breaths through an endotracheal tube. When an alarm sounds, the patient comes first — not the machine.

01 · Alarm + distressCan't find the cause fast: bag with 100% O₂
02 · Pressure alarmsHigh = obstruction · low = leak or disconnect
03 · Which settingFiO₂ + PEEP fix O₂ · rate + volume fix CO₂
01

Settings: what fixes what

FiO₂ and PEEP fix oxygenation · rate and tidal volume fix ventilation

Low PaO₂ or SpO₂ → adjust FiO₂ or PEEP
PaCO₂ or pH off → adjust rate or tidal volume
Titrate FiO₂ to the lowest that keeps SpO₂ 94% or higher
CO₂ retainers (COPD): target SpO₂ 88–92%
Tidal volume 6–8 mL/kg of ideal body weight
PEEP usually starts at 5 cm H₂O — keeps alveoli open
PEEP = pressure held at end-exhalation; PIP = peak of the breath
Draw an ABG 20–30 minutes after starting or changing settings

Keep plateau pressure below 30 cm H₂O to prevent overdistension lung injury. ICU SpO₂ targets vary (StatPearls: 90–96%); the point is avoiding both hypoxemia and needless high oxygen.

02

Ventilator modes

Assist-control (AC): every breath gets the full set tidal volume
AC + tachypnea → respiratory alkalosis and auto-PEEP
SIMV: a set number of full breaths; extra breaths at own volume
Pressure support (PS): boosts each breath the patient starts
PS has no set rate — needs an intact respiratory drive

Pressure support is used for weaning. Classic texts call SIMV a weaning mode; current ICU practice weans mainly with pressure support or T-piece trials.

03

Before: confirm the tube

End-tidal CO₂ — the most objective check
Equal bilateral breath sounds and chest rise
Chest X-ray
Note the tube's cm marking at the lips or teeth
04

During: daily care

Head of bed 30–45° to prevent ventilator-associated pneumonia
Recheck the tube's cm marking after moving the patient
Tube migration → right mainstem intubation or extubation
Watch BP after PEEP goes up — less venous return
Give a communication board or pen and paper
05

When an alarm sounds

Assess the patient first, then the machine

Assess the patient first
Distress + cause not found fast → disconnect, bag with 100% O₂ bag now
Apnea alarm: no breaths detected — check for oversedation

Causes of sudden deterioration on the ventilator — DOPE: Displacement, Obstruction, Pneumothorax, Equipment failure.

06

High or low pressure alarm?

High = something blocks the breath · low = air is escaping

High pressureLow pressure
MeansObstruction, resistance or a stiff chestLeak or disconnection
CausesSecretions, kinked tube, biting, coughing, bronchospasm, pneumothoraxCircuit off, cuff leak, extubation
07

Red flags

Tension pneumothorax: one side silent, trachea shifted, low BP, JVD needle decompression
Hypotension after a PEEP increase report now
Stridor after extubation → laryngeal edema ready to reintubate

Tension pneumothorax comes from barotrauma: sudden distress, absent breath sounds on one side, the trachea deviated away from that side.

08

After: weaning and extubation

Ready when the cause is improving and oxygen needs are low — FiO₂ 40% or less

Ready: cause improving, awake, hemodynamically stable
Ready: oxygen need low — FiO₂ 40% or less
Then a spontaneous breathing trial (SBT)
Stop the SBT: RR over 35, HR over 140, SpO₂ under 90%, distress resume support
After extubation, watch closely for stridor for the first hours

Protocols vary: the AHRQ SAT/SBT safety screen fails a patient on FiO₂ 50% or more with PEEP 8 or more.

09

Nursing priorities

Alarm: assess the patient first — bag with 100% O₂ if in distress
Confirm and secure the tube: ETCO₂, breath sounds, cm marking
Keep the head of the bed at 30–45°
Watch BP after PEEP increases
Draw an ABG 20–30 minutes after any setting change
10

Teach your patient

You can't speak — the tube passes through the vocal cords
Use the communication board or pen and paper
Pearl

Vent alarm? Look at the patient first — in distress with no fast fix, bag with 100% O₂. High pressure = blocked · low pressure = leak.

Sources · Ventilator Management (StatPearls) · Assist-Control Ventilation (StatPearls) · Synchronized Intermittent Mandatory Ventilation (StatPearls) · Invasive Mechanical Ventilation (StatPearls) · Medical-Surgical Nursing 35.3 Respiratory Concerns (OpenStax) · Endotracheal Tube (StatPearls) · Adding an R in the DOPE Mnemonic (PMC) · Low-pressure alarm causes (PMC) · Post-Intubation Laryngeal Edema (StatPearls) · Tension Pneumothorax (StatPearls) · Oxygenation Status and Pulse Oximeter Analysis (StatPearls) · Oxygen therapy in COPD exacerbations (PMC) · Strategies to prevent VAP, 2022 update (SHEA/IDSA/APIC) · Sampling for Arterial Blood Gas Analysis (AARC) · Identifying patients capable of breathing spontaneously (NEJM 1996) · Spontaneous Awakening and Breathing Trials Protocol (AHRQ) · Ventilator Safety (StatPearls) · Mechanical Ventilation Protocol Summary (NHLBI ARDS Network) · Follow your facility's protocol for ventilator weaning.

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