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Malnutrition Identification & Intervention

Malnutrition identification goes beyond screening to clinical diagnosis and response. The AND/ASPEN consensus criteria require two or more of the following indicators; weight loss is judged against onset, not absolute number, and fluid accumulation can mask true muscle and fat loss.

Albumin vs prealbumin as nutrition markers

AlbuminPrealbumin
Normal range3.5-5.0 g/dL15-36 mg/dL
Half-life~20 days2-3 days
ReflectsWeeks-old status, disease severityRecent nutritional change
Drops with inflammationYesYes

Albumin

Normal range
3.5-5.0 g/dL
Half-life
~20 days
Reflects
Weeks-old status, disease severity
Drops with inflammation
Yes

Prealbumin

Normal range
15-36 mg/dL
Half-life
2-3 days
Reflects
Recent nutritional change
Drops with inflammation
Yes
Daily weight
same time, same scale, same clothing
Strict intake and output
72-hour calorie count
Serum prealbumin trend
responds in 2-3 days

Feeding route hierarchy — if the gut works, use it

  1. Oral supplementssmall frequent meals, oral care before eating
  2. Enteral nutritionpreferred when gut is functional
  3. Parenteral nutritiononly when gut nonfunctional
Oral care before meals
improves appetite
Small frequent meals
Sit upright 30-60 minutes after eating
Dietitian collaboration
Report Nowescalate immediately
Severe rapid weight loss with poor intake
Profound muscle wasting
Pressure injury or poor wound healing
Refeeding syndrome Hallmark
falling phosphate, potassium, magnesium when feeding a starved patient
Hypophosphatemia on refeeding
leading cause of refeeding death
Verify thiamine before first feeding
prevents Wernicke encephalopathy

Clinical Pearl

Unintentional weight loss + muscle wasting + low prealbumin flags malnutrition — and feed the starved patient SLOWLY, with baseline phosphate/K+/Mg and thiamine, to avoid refeeding syndrome.

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