Meningitis
Pathophysiology & Risk Factors
Inflammation of the meninges from bacterial, viral, or fungal organisms. Bacterial meningitis (most often Neisseria meningitidis or Streptococcus pneumoniae) is a medical emergency with 15-30% mortality even when treated; viral meningitis is usually self-limiting.
Signs & Symptoms
Diagnostics & Labs
CSF findings: bacterial vs viral meningitis
Bacterial
- Appearance
- cloudy / turbid
- WBC differential
- neutrophil predominance
- Protein
- markedly elevated
- Glucose
- decreased
- Opening pressure
- elevated
Viral
- Appearance
- clear
- WBC differential
- lymphocyte predominance
- Protein
- normal to mildly elevated
- Glucose
- normal
- Opening pressure
- normal to mildly elevated
Interventions & Priorities
Treatments & Medications
Patient Teaching
Complications
Clinical Pearl
Kernig = Knee (can't straighten it); Brudzinski = Brain-to-knee (flex the neck, the knees follow). Bacterial CSF is cloudy with LOW glucose; viral is clear with NORMAL glucose.