Stroke Types: Ischemic vs Hemorrhagic — Treatment Is Opposite
Giving tPA to a hemorrhagic stroke patient accelerates fatal bleeding. Giving nothing to an ischemic stroke patient lets brain tissue die. The CT scan result flips your entire plan — choosing wrong is catastrophic, and the NCLEX knows it.
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Comparison
- Clot blocks a cerebral artery
- ~87% of all strokes
- Vessel ruptures, bleeds into brain
- ~13% of all strokes
- Gradual/stuttering onset
- mild or no headache
- Sudden explosive onset
- thunderclap headache
- CT negative for blood (rules out bleed pre-tPA)
- Blood visible immediately on CT
- Activate stroke team
- CT STAT
- Assess tPA eligibility
- neuro checks q15 min
- Activate stroke team
- CT STAT
- Manage BP & ICP
- prep surgery
- neuro q15 min
- ★tPA/alteplase if within 4.5 hr + CT clear
- Thrombectomy ≤24 hr
- antiplatelets, statin
- ★tPA CONTRAINDICATED — worsens bleed
- Reverse anticoagulation
- nimodipine for SAH
- ★Permissive HTN pre-tPA ≤220/120
- <180/105 after
- Adhere to antiplatelets
- control risk factors
- ★Lower BP aggressively
- SBP < 140
- Avoid Valsalva
- manage HTN long-term
- Cerebral edema then ↑ ICP after large infarct
- Bleeding signs post-tPA then hold, CT
- High ICP expected — elevate HOB 30°
- Head midline
- rebleed/herniation signs
- Lower acute seizure risk
- Hemorrhagic conversion after reperfusion
- Higher seizure risk — blood irritates cortex
- Rebleed, vasospasm (SAH), hydrocephalus
Ischemic Stroke
- Clot blocks a cerebral artery
- ~87% of all strokes
Hemorrhagic Stroke
- Vessel ruptures, bleeds into brain
- ~13% of all strokes
Ischemic Stroke
- Gradual/stuttering onset
- mild or no headache
Hemorrhagic Stroke
- Sudden explosive onset
- thunderclap headache
Ischemic Stroke
- CT negative for blood (rules out bleed pre-tPA)
Hemorrhagic Stroke
- Blood visible immediately on CT
Ischemic Stroke
- Activate stroke team
- CT STAT
- Assess tPA eligibility
- neuro checks q15 min
Hemorrhagic Stroke
- Activate stroke team
- CT STAT
- Manage BP & ICP
- prep surgery
- neuro q15 min
Ischemic Stroke
- ★tPA/alteplase if within 4.5 hr + CT clear
- Thrombectomy ≤24 hr
- antiplatelets, statin
Hemorrhagic Stroke
- ★tPA CONTRAINDICATED — worsens bleed
- Reverse anticoagulation
- nimodipine for SAH
Ischemic Stroke
- ★Permissive HTN pre-tPA ≤220/120
- <180/105 after
- Adhere to antiplatelets
- control risk factors
Hemorrhagic Stroke
- ★Lower BP aggressively
- SBP < 140
- Avoid Valsalva
- manage HTN long-term
Ischemic Stroke
- Cerebral edema then ↑ ICP after large infarct
- Bleeding signs post-tPA then hold, CT
Hemorrhagic Stroke
- High ICP expected — elevate HOB 30°
- Head midline
- rebleed/herniation signs
Ischemic Stroke
- Lower acute seizure risk
- Hemorrhagic conversion after reperfusion
Hemorrhagic Stroke
- Higher seizure risk — blood irritates cortex
- Rebleed, vasospasm (SAH), hydrocephalus
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No blood on CT → clot → tPA candidate. Blood on CT → bleed → tPA kills.
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