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NurseSavvy Cheat SheetDisease

Alzheimer's Disease & Dementia — Nursing Care

Alzheimer's disease is the most common cause of dementia (60-80% of cases): a progressive, irreversible decline in cognition that moves through predictable stages. The stage drives the safety priority — early disease centers on medication safety and driving, the moderate stage on wandering and elopement, and the late stage on aspiration, skin integrity, and comfort. The hallmark of the moderate stage is the 3 A's: aphasia, apraxia, and agnosia.

Delirium vs Dementia — a sudden change is delirium until proven otherwise

DeliriumDementia
OnsetAcute (hours to days)Gradual (months to years)
CourseReversibleIrreversible, progressive
TriggerInfection, drugs, metabolicNeurodegeneration
Nursing responseFind and treat the causeSupport function and safety

Delirium

Onset
Acute (hours to days)
Course
Reversible
Trigger
Infection, drugs, metabolic
Nursing response
Find and treat the cause

Dementia

Onset
Gradual (months to years)
Course
Irreversible, progressive
Trigger
Neurodegeneration
Nursing response
Support function and safety
EarlyProgresses →
Recent (short-term) memory loss Hallmark
Word-finding difficulty
Misplacing objects
Getting lost in familiar places
Late / Severe
Aphasia
3 A's — can't find words
Apraxia
3 A's — can't perform learned tasks
Agnosia
3 A's — can't recognize faces/objects
Wandering Hallmark
peaks in moderate stage
Sundowning
late-afternoon confusion/agitation
Incontinence
Total ADL dependence
Dysphagia
Mini-Mental State Exam (MMSE)score <= 23 suggests impairment
Montreal Cognitive Assessment (MoCA)
Clinical diagnosis of exclusion
rule out reversible causes first
Assess for reversible triggers Hallmark
pain, infection, constipation, toileting needs — do this first
Secure the environment
ID bracelet, door alarms, bed alarm, locked unit
Validation therapy + redirection
moderate-to-severe stage; do not argue
Reality orientation
early stage only
Simple one-step commands
Consistent daily routine
Manage sundowning environmentally
adequate lighting, reduce stimuli — not restraints
Offer finger foods
maintains intake in the wandering client
DonepezilPrototype
cholinesterase inhibitor
Rivastigmine
cholinesterase inhibitor
Galantamine
cholinesterase inhibitor
Memantine
NMDA-receptor antagonist
Home safety measures
remove clutter, secure exits, reduce fall hazards
Maintain consistent routines
Use door alarms, not restraints
Disease is progressive, not stabilizing
loss of recognition will keep worsening
Caregiver support and respite
watch for caregiver burnout
Establish advance directives early
Falls and injury
Aspiration pneumonia
Malnutrition and dehydration
Pressure injury
bedbound late stage
Caregiver burnout
Report Nowescalate immediately
Antipsychotic for agitationBlack Box
boxed warning: increased mortality in elderly dementia; last resort only
Sudden change in cognition Hallmark
rule out delirium/infection — delirium until proven otherwise
Wandering / elopement
found off-unit, exit-seeking
Signs of aspiration
dysphagia in late stage
Suspected caregiver abuse or neglect
PRN benzodiazepine for agitationHold
raises fall risk + paradoxical agitation; not first-line

Clinical Pearl

Protect safety and preserve dignity — and a sudden change in a dementia client is delirium until proven otherwise.

NurseSavvy™·nursesavvy.com

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