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NurseSavvy Cheat SheetDisease

GI Bleeding — Upper vs Lower

GI bleeding is classified by its origin relative to the ligament of Treitz. Upper bleeds (above the landmark — esophagus, stomach, duodenum) typically produce hematemesis and melena; lower bleeds (below — colon, rectum) typically produce hematochezia. A brisk upper bleed can also produce hematochezia, so bright-red rectal bleeding with hemodynamic instability should raise suspicion for an upper source.

Upper vs Lower GI Bleed

Upper GI bleedLower GI bleed
Source (vs ligament of Treitz)Above — esophagus, stomach, duodenumBelow — colon, rectum
Common causesPUD, varices, gastritisDiverticulosis, angiodysplasia, hemorrhoids, cancer
EmesisHematemesis (bright red or coffee-ground)None
StoolMelena (black, tarry, foul)Hematochezia (bright red or maroon)
BUN:Cr ratioElevated >20:1 (digested blood)Less elevated
Definitive workupEGD / upper endoscopyColonoscopy

Upper GI bleed

Source (vs ligament of Treitz)
Above — esophagus, stomach, duodenum
Common causes
PUD, varices, gastritis
Emesis
Hematemesis (bright red or coffee-ground)
Stool
Melena (black, tarry, foul)
BUN:Cr ratio
Elevated >20:1 (digested blood)
Definitive workup
EGD / upper endoscopy

Lower GI bleed

Source (vs ligament of Treitz)
Below — colon, rectum
Common causes
Diverticulosis, angiodysplasia, hemorrhoids, cancer
Emesis
None
Stool
Hematochezia (bright red or maroon)
BUN:Cr ratio
Less elevated
Definitive workup
Colonoscopy
EarlyProgresses →
Hematemesis Hallmark
bright red or coffee-ground emesis
Coffee-ground emesis Hallmark
blood exposed to gastric acid; upper source
Melena Hallmark
black, tarry, foul stool; digested blood, upper source
Hematochezia
bright red/maroon rectal blood; usually lower
Tachycardia Hallmark
earliest sign of significant blood loss
Orthostatic vital sign changes
SBP drop >=20, DBP drop >=10, or pulse rise >=20 on standing
Late / Severe
Pallor
Diaphoresis
Hypotension
follows tachycardia
Falling hemoglobin and hematocrit
lags 6-24 hr behind acute loss

Monitor

Hemoglobin and hematocrit
lag 6-24 hr; do not rule out acute bleed if normal
Coagulation panel / INR
quantify and guide anticoagulation reversal

Diagnostic

BUN-to-creatinine ratioBUN:Cr > 20:1
elevated with normal Cr suggests upper source
Type and crossmatch
obtain early for blood availability
Stool occult blood (guaiac)
confirms bleeding when not visible
Upper endoscopy (EGD)
locates/treats upper source
Colonoscopy
locates lower source after stabilization
Assess airway and aspiration risk
do not lay an actively vomiting client supine
Two large-bore IV lines
16-18 gauge for rapid volume resuscitation
Isotonic crystalloid bolus
restore perfusion pressure
Maintain NPO status
reduce aspiration; prepare for endoscopy
Continuous hemodynamic monitoring
trend HR, BP, urine output
Prepare blood products
type and cross; transfuse per shock indicators, not H&H alone
Prepare for endoscopy
EGD or colonoscopy after stabilization
IV proton pump inhibitor
for upper GI bleed; suppresses acid
Octreotide
reduces portal pressure in variceal bleeding
Endoscopic variceal banding
definitive control of varices
Packed red blood cells
restrictive target ~7-9 g/dL; liberal >10 raises rebleed risk
Reverse anticoagulation
guided by INR in active bleeding

Contraindications

Avoid lactated Ringer's with bloodHold
LR's calcium causes blood to clot; normal saline is the ONLY compatible solution for priming/infusing blood.
Avoid NSAIDs
all NSAIDs erode gastric mucosa, OTC or not
Use acetaminophen for pain
no antiplatelet/mucosal effect
Read OTC labels for hidden NSAIDs/aspirin
combination cold/headache products
Avoid alcohol
Complete H. pylori treatment
if ulcer-related
Recognize signs of rebleeding
black stools, bloody emesis, weakness, dizziness
Report Nowescalate immediately
Hemodynamic instability
persistent tachycardia + hypotension after fluids
Persistent tachycardia despite resuscitation
earliest sign of ongoing hemorrhage
OliguriaUO < 0.5 mL/kg/hr
inadequate perfusion
Active hematemesis
Hematochezia with instability
suspect massive upper GI bleed
Ongoing melena
Falling hemoglobin and hematocrit
after dilution; confirms loss
Signs of hypovolemic shock
cool, pale, diaphoretic skin

Clinical Pearl

Hematemesis + melena + a high BUN:Cr points upper; bright-red rectal bleeding points lower. Tachycardia rises before the BP falls — resuscitate before you scope.

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