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NurseSavvy Cheat SheetDisease

GERD

GERD develops when the lower esophageal sphincter (LES) relaxes inappropriately or maintains inadequate tone, allowing gastric acid to repeatedly contact esophageal mucosa. Unlike occasional heartburn, this chronic exposure can progress to esophagitis and metaplastic change.

Pyrosis HallmarkEarly
substernal burning, worse after meals and supine
Sour regurgitationEarly
sour or bitter fluid
Chronic coughEarly
atypical, delays diagnosis
HoarsenessEarly
atypical presentation
Non-cardiac chest painEarly
post-meal, relieved by antacids

GERD vs cardiac chest pain

FeatureGERD painCardiac pain
TimingTimingAfter meals, when supineWith exertion
ReliefReliefAntacids relieveRequires immediate workup
RadiationRadiationLocalized substernalRadiates (arm/jaw)
DiaphoresisDiaphoresisAbsentOften present

Feature

Timing
Timing
Relief
Relief
Radiation
Radiation
Diaphoresis
Diaphoresis

GERD pain

Timing
After meals, when supine
Relief
Antacids relieve
Radiation
Localized substernal
Diaphoresis
Absent

Cardiac pain

Timing
With exertion
Relief
Requires immediate workup
Radiation
Radiates (arm/jaw)
Diaphoresis
Often present
Proton pump inhibitorsPrototype
first-line; omeprazole, pantoprazole
H2 receptor antagonists
second-line; famotidine
Antacids
neutralize existing acid; not interchangeable with PPIs

PPI timing for acid suppression

  1. Take PPI30-60 min before first meal
  2. Eat first mealfood activates proton pumps
  3. Peak suppressiondrug binds actively secreting pumps
Esophagitis
Barrett esophagus
squamous-to-columnar metaplasia; premalignant
Esophageal adenocarcinoma
increased risk from Barrett changes
Report Nowescalate immediately
Dysphagia
alarm feature; Barrett/cancer workup
Odynophagia
painful swallowing
Unintentional weight loss
alarm feature
GI bleeding
hematemesis or melena
Bone pain on long-term PPI
osteoporosis/fracture risk
Muscle cramps on long-term PPI
hypomagnesemia

Clinical Pearl

Blocks, not pillows: raise the bed frame 6-8 inches at the head so gravity keeps acid in the stomach all night long.

NurseSavvy™·nursesavvy.com

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