Diverticular Disease
Pathophysiology & Risk Factors
Diverticula are false outpouchings of colonic mucosa and submucosa that herniate through weak points in the muscular wall, most commonly in the sigmoid colon. Diverticulosis is the asymptomatic presence of these pouches; diverticulitis is inflammation or microperforation of a diverticulum ("-osis is quiet, -itis is angry"). Risk rises sharply after age 60.
Diverticulosis vs diverticulitis
Diverticulosis (-osis)
- State
- Pouches present, no inflammation
- Symptoms
- Often asymptomatic; painless bleeding
- Diet
- High-fiber to PREVENT (25-35 g/day)
- Colonoscopy
- Used to diagnose incidentally
Diverticulitis (-itis)
- State
- Inflamed / microperforated pouch
- Symptoms
- LLQ pain, fever, leukocytosis
- Diet
- NPO/clear liquids, rest the bowel
- Colonoscopy
- Contraindicated in acute phase
Signs & Symptoms
Diagnostics & Labs
Diagnostic
Monitor
Interventions & Priorities
Treatments & Medications
Patient Teaching
Complications
Clinical Pearl
"-osis is quiet, -itis is angry." Quiet colon gets fiber; angry colon gets rest — never scope an angry colon, and never give it morphine.