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NurseSavvy Cheat SheetDisease

Hyponatremia

Hyponatremia is serum sodium below 135 mEq/L. Sodium is the primary extracellular electrolyte controlling water balance, so low sodium usually means too much water relative to sodium — diluted blood. Water shifts into cells by osmosis, swelling them; the brain is most vulnerable because the skull confines it. Symptoms track how fast sodium falls, not just how low it goes.

EarlyProgresses →
Often asymptomatic
mild, Na 130-134 mEq/L
Nausea
Headache
Confusion
moderate, Na 120-129 mEq/L
Lethargy
Late / Severe
Seizures Hallmark
severe, Na < 120 mEq/L
Coma
Respiratory arrest
Neuro symptom zone
Lower normal
Severe (seizures, coma)
Hyponatremia
Normal
110
120
135
145

mEq/L

Implement seizure precautions
padded rails, lowest bed position when Na < 120
Protect airway and monitor LOC
Assess volume status first
dilutional vs depletional drives opposite treatment
Restrict fluids for dilutional cause
first-line for SIADH/euvolemic; typically 1,000-1,500 mL/day
Replace sodium slowly
no faster than 8-12 mEq/L per 24 h

Same Na+, opposite treatment — volume status decides

HypovolemicEuvolemic (SIADH)Hypervolemic
Exam findingsPoor turgor, dry membranes, orthostasisNo edema, no orthostatic changesPedal edema, JVD, crackles
Water balanceSodium loss > water lossFree water retentionWater retained > sodium
Treatment0.9% normal salineFluid restrictionFluid restriction + diuretics

Hypovolemic

Exam findings
Poor turgor, dry membranes, orthostasis
Water balance
Sodium loss > water loss
Treatment
0.9% normal saline

Euvolemic (SIADH)

Exam findings
No edema, no orthostatic changes
Water balance
Free water retention
Treatment
Fluid restriction

Hypervolemic

Exam findings
Pedal edema, JVD, crackles
Water balance
Water retained > sodium
Treatment
Fluid restriction + diuretics
Adhere to prescribed fluid restriction
Do not restrict dietary sodium
restrict water, not salt, in dilutional type
Report new confusion or headache
Review medications that lower sodium
thiazides especially
Osmotic demyelination syndrome Hallmark
central pontine myelinolysis; irreversible — from correcting TOO fast, not from the low sodium
Cerebral edema
water into brain cells raises intracranial pressure
Report Nowescalate immediately
Seizure activity Hallmark
Serum sodium < 120 mEq/LNa+ < 120 mEq/L
Worsening confusion or decreasing LOC
Bradycardia with rising blood pressure
rising intracranial pressure from cerebral edema
Persistent vomiting with neuro changes
central origin from cerebral edema
Sodium rising > 8-12 mEq/L per 24 hΔNa+ > 12 mEq/L / 24 h
overcorrection risks osmotic demyelination

Clinical Pearl

Low sodium = swollen, waterlogged brain. Restrict water first, replace sodium slowly — correcting too fast is the real danger.

NurseSavvy™·nursesavvy.com

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