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side by side comparison

Potassium Imbalance: Hypokalemia vs Hyperkalemia — ECG, Symptoms, Interventions

A potassium of 3.0 and a potassium of 6.5 both trigger lethal dysrhythmias, but the ECG patterns, symptoms, and emergency interventions are mirror opposites. Picking the wrong correction on the NCLEX means choosing the action that kills the patient.

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Comparison

Side-by-side2 compared
Focus
Dimension
Hypokalemia (< 3.5)
Hyperkalemia (> 5.0)
Pathophysiology & risk
  • Loop / thiazide diuretics
  • Vomiting, NG suction
  • Alkalosis
  • insulin administration
  • Renal failure
  • K⁺-sparing diuretics (spironolactone)
  • Crush injury
  • acidosis
  • transfusion
Signs & symptoms
  • Muscle weakness
  • Leg cramps
  • Hyporeflexia
  • ↓ GI motility, ileus
  • Muscle weakness
  • Muscle twitching, paresthesias
  • Ascending flaccid paralysis
  • Intestinal cramping, diarrhea
Diagnostics & labs
  • Serum K⁺ < 3.5
  • flat/inverted T waves
  • ★Prominent U waves
  • ST depression
  • ★Tall peaked T waves (early)
  • Serum K⁺ >5.0
  • widened QRS, loss of P
Nursing priorities
  • Continuous telemetry
  • Check Mg²⁺: low Mg blocks K⁺ repletion
  • KCl is a vesicant — check IV site
  • Continuous telemetry
  • Recheck K⁺ 1 hr post-treatment
  • Watch rebound hypokalemia after insulin
Treatment / meds
  • ★IV KCl ≤10 mEq/hr peripheral
  • never IV push
  • Always use an infusion pump
  • ★IV calcium gluconate first
  • Insulin + dextrose, bicarb
  • K⁺ binders, dialysis
Patient teaching
  • Eat K⁺-rich foods (bananas, potatoes)
  • Restrict K⁺-rich foods
  • read labels
  • Avoid salt substitutes (contain KCl)
Red flags — escalate
  • PVCs, V-tach, V-fib
  • Potentiates digoxin toxicity
  • Bradycardia, heart block, asystole
  • Risk spikes when K⁺ > 6.5
Complications
  • Cardiac arrest (V-fib)
  • paralytic ileus
  • Sine-wave QRS pattern
  • Cardiac arrest (asystole)
Pathophysiology & risk

Hypokalemia (< 3.5)

  • Loop / thiazide diuretics
  • Vomiting, NG suction
  • Alkalosis
  • insulin administration

Hyperkalemia (> 5.0)

  • Renal failure
  • K⁺-sparing diuretics (spironolactone)
  • Crush injury
  • acidosis
  • transfusion
Signs & symptoms

Hypokalemia (< 3.5)

  • Muscle weakness
  • Leg cramps
  • Hyporeflexia
  • ↓ GI motility, ileus

Hyperkalemia (> 5.0)

  • Muscle weakness
  • Muscle twitching, paresthesias
  • Ascending flaccid paralysis
  • Intestinal cramping, diarrhea
Diagnostics & labs

Hypokalemia (< 3.5)

  • Serum K⁺ < 3.5
  • flat/inverted T waves
  • ★Prominent U waves
  • ST depression

Hyperkalemia (> 5.0)

  • ★Tall peaked T waves (early)
  • Serum K⁺ >5.0
  • widened QRS, loss of P
Nursing priorities

Hypokalemia (< 3.5)

  • Continuous telemetry
  • Check Mg²⁺: low Mg blocks K⁺ repletion
  • KCl is a vesicant — check IV site

Hyperkalemia (> 5.0)

  • Continuous telemetry
  • Recheck K⁺ 1 hr post-treatment
  • Watch rebound hypokalemia after insulin
Treatment / meds

Hypokalemia (< 3.5)

  • ★IV KCl ≤10 mEq/hr peripheral
  • never IV push
  • Always use an infusion pump

Hyperkalemia (> 5.0)

  • ★IV calcium gluconate first
  • Insulin + dextrose, bicarb
  • K⁺ binders, dialysis
Patient teaching

Hypokalemia (< 3.5)

  • Eat K⁺-rich foods (bananas, potatoes)

Hyperkalemia (> 5.0)

  • Restrict K⁺-rich foods
  • read labels
  • Avoid salt substitutes (contain KCl)
Red flags — escalate

Hypokalemia (< 3.5)

  • PVCs, V-tach, V-fib
  • Potentiates digoxin toxicity

Hyperkalemia (> 5.0)

  • Bradycardia, heart block, asystole
  • Risk spikes when K⁺ > 6.5
Complications

Hypokalemia (< 3.5)

  • Cardiac arrest (V-fib)
  • paralytic ileus

Hyperkalemia (> 5.0)

  • Sine-wave QRS pattern
  • Cardiac arrest (asystole)

★ marks the fact that sets a column apart.

Clinical Pearl

Flat T = low K⁺; peaked T = high K⁺ — the T wave mirrors the potassium level.

Component Topics

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