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NurseSavvy Cheat SheetDisease

Parasitic Infections — Pinworm, Giardia, Toxoplasmosis

Pinworm (Enterobius vermicularis) is the most common helminth in the US, mainly in school-age children, spread fecal-orally with autoinoculation (scratch-to-mouth); eggs stay viable on surfaces 2-3 weeks. Giardia is the most common parasitic cause of US diarrhea, a protozoan from contaminated water whose cysts resist standard chlorination. Toxoplasma gondii is an intracellular protozoan with the cat as definitive host; pregnancy and immunocompromised (HIV CD4 <100) are the danger groups.

Perianal pruritus Hallmark
pinworm; worse at night
Disrupted sleep
child scratching overnight
Foul greasy floating stools Hallmark
giardia steatorrhea, no blood/mucus
Bloating
giardia
Flatulence
giardia
Abdominal cramping
Mononucleosis-like illness
toxoplasma in immunocompetent; often asymptomatic
Cellophane tape test Hallmark
pinworm; early morning before bathing/toileting
Stool O&P unreliable for pinworm
eggs on perianal skin, not in stool
Stool O&P for giardia
may need 3 specimens; intermittent shedding
Stool antigen test
giardia; more sensitive
Ring-enhancing brain lesion
toxoplasma on MRI in HIV/AIDS

Pinworm vs Giardia vs Toxoplasmosis

PinwormGiardiaToxoplasmosis
OrganismHelminth (worm)ProtozoanProtozoan
Hallmark signNighttime perianal itchFoul greasy diarrheaOften asymptomatic
DiagnosisMorning tape testStool O&P / antigenMRI ring lesion / serology
TreatmentMebendazole, repeat x2wkMetronidazolePyrimethamine + sulfadiazine
Key teachingTreat whole householdNo alcohol on metronidazoleAvoid litter box in pregnancy

Pinworm

Organism
Helminth (worm)
Hallmark sign
Nighttime perianal itch
Diagnosis
Morning tape test
Treatment
Mebendazole, repeat x2wk
Key teaching
Treat whole household

Giardia

Organism
Protozoan
Hallmark sign
Foul greasy diarrhea
Diagnosis
Stool O&P / antigen
Treatment
Metronidazole
Key teaching
No alcohol on metronidazole

Toxoplasmosis

Organism
Protozoan
Hallmark sign
Often asymptomatic
Diagnosis
MRI ring lesion / serology
Treatment
Pyrimethamine + sulfadiazine
Key teaching
Avoid litter box in pregnancy
Standard precautions
Meticulous hand hygiene Hallmark
before meals and after toileting
Treat entire household simultaneously Hallmark
pinworm; eliminate asymptomatic carriers
Launder bedding in hot water
daily during pinworm treatment
Keep fingernails short
reduces pinworm autoinoculation
Tape test before bathing
first thing in morning
Repeat pinworm dose in 2 weeks Hallmark
kills newly hatched worms
Avoid alcohol on metronidazole
during and 48-72h after; disulfiram-like reaction
Delegate litter box in pregnancy Hallmark
cat stays, litter duty goes
Cook meat to safe temperature
no rare/medium-rare
Wear gloves when gardening
toxoplasma oocysts in soil
Wash all produce
Report Nowescalate immediately
Severe dehydration
heavy giardia diarrhea
Disulfiram-like reaction
metronidazole + alcohol: flushing, vomiting, tachycardia
New seizures
CNS toxoplasmosis (in-scope); or neurocysticercosis from pork tapeworm
Toxoplasma exposure in pregnancy
congenital infection risk
Anemia or malnutrition
heavy systemic infestation

Clinical Pearl

Pinworm = nighttime perianal itch, a morning tape test, and treat the whole household; Giardia = greasy diarrhea from bad water (metronidazole, no alcohol); Toxo in pregnancy = the cat stays, the litter box duty goes.

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