Hypertensive Crisis
Pathophysiology & Risk Factors
Hypertensive crisis is a BP above 180/120 mmHg. The critical split is NOT the number — it is the presence or absence of acute end-organ damage. Urgency = severely elevated BP with no organ damage (oral meds, gradual reduction over 24-48 hr). Emergency = the same pressure actively destroying target organs (IV meds, ICU). Because the brain has autoregulated to chronically high pressures, lowering BP too fast starves it (watershed ischemia).
Urgency vs emergency — distinguished by organ damage, not BP number
Hypertensive urgency
- End-organ damage
- Absent
- Setting
- Outpatient / observation
- Medication route
- Oral (captopril, labetalol PO)
- Reduction goal
- Gradual over 24-48 hr
Hypertensive emergency
- End-organ damage
- Present
- Setting
- ICU
- Medication route
- IV titratable (nicardipine, labetalol, nitroprusside)
- Reduction goal
- MAP down ≤25% in first hour
Signs & Symptoms
Diagnostics & Labs
Monitor
Diagnostic
Interventions & Priorities
% MAP reduction in first hour
Treatments & Medications
Patient Teaching
Complications
Clinical Pearl
Urgency = high number, no damage, oral meds, slow. Emergency = organs screaming, IV drip, ICU — and never drop MAP more than 25% in the first hour.