Aortic Valve Disorders
Pathophysiology & Risk Factors
Aortic valve disorders are two opposite mechanical problems. In aortic stenosis (AS) the valve opening narrows (normal 3-4 cm2; severe < 1.0 cm2), so the left ventricle must generate higher pressure to eject, producing a systolic murmur and a narrow pulse pressure. In aortic regurgitation (AR) the valve fails to seal, allowing diastolic backflow into the LV, producing a diastolic murmur, chronic volume overload, LV dilation, and a wide pulse pressure.
Signs & Symptoms
Diagnostics & Labs
Aortic stenosis vs regurgitation
Aortic stenosis
- Valve problem
- Fails to open (narrowed)
- Murmur timing
- Systolic crescendo-decrescendo
- Best heard
- Right 2nd ICS, radiates to carotids
- Pulse pressure
- Narrow
- Ventricular response
- LV hypertrophy
Aortic regurgitation
- Valve problem
- Fails to close (leaky)
- Murmur timing
- Diastolic decrescendo
- Best heard
- Left sternal border
- Pulse pressure
- Wide (water-hammer)
- Ventricular response
- LV dilation
Interventions & Priorities
Treatments & Medications
Patient Teaching
Complications
Clinical Pearl
Stenosis squeezes the pressure narrow; regurgitation lets it run wide. Match the murmur to the valve: systolic = stenosis, diastolic = regurgitation.